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Article

Ancient viral DNA in the human genome linked to neurodegenerative diseases.

Brain, behavior, and immunity - 1 Jan 2025

Duarte Rodrigo R R, Nixon Douglas F, Powell Timothy R

Abstract excerpt

BACKGROUND: Human endogenous retroviruses (HERVs) are sequences in the human genome that originated from infections with ancient retroviruses during our evolution. Previous studies have linked HERVs to neurodegenerative diseases, but defining their role in aetiology has been challenging. Here, we used a retrotranscriptome-wide association study (rTWAS) approach to assess the relationships between genetic risk for...

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Identifiers

PMID: 39401554
DOI: 10.1016/j.bbi.2024.10.020

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

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