Article

Extracellular vesicles improve GABAergic transmission in Huntington’s disease iPSC-derived neurons

2022-12-18

Abstract excerpt

Extracellular vesicles (EVs) carry bioactive molecules associated with various biological processes, including miRNAs. In both Huntington’s disease (HD) models and human samples, altered expression of miRNAs involved in synapse regulation were reported. Recently, the use of EV cargo to reverse phenotypic alterations in disease models with synaptopathy as the end-result of the pathophysiological cascade has become...

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Literature Corpus work: c68fe1da-a6f5-5322-b6b3-5654dbd0cd62
DOI: 10.1101/2022.12.18.520919

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