Article

Exosomes regulate Neurogenesis and Circuit Assembly in a Model of Rett Syndrome

2017-07-26

Abstract excerpt

<h4>Summary</h4> Exosomes are thought to be secreted by all cells in the body and to be involved in intercellular communication. Here, we tested whether neural exosomes regulate the development of neural circuits and whether exosome-mediated signaling may be aberrant in the neurodevelopmental disorder Rett Syndrome (RTT). Quantitative proteomic analysis comparing exosomes from human induced pluripotent stem cells...

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Literature Corpus work: 80fbc0e5-f8e9-51e5-9aee-13133d13f34c
DOI: 10.1101/168955

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