Article

iPSC-derived healthy human astrocytes selectively load miRNAs targeting neuronal genes into extracellular vesicles

2023-04-29

Abstract excerpt

Astrocytes are in constant communication with neurons during the establishment and maturation of functional networks in the developing brain. Astrocytes release extracellular vesicles (EVs) containing microRNA (miRNA) cargo that regulates transcript stability in recipient cells. Astrocyte released factors are thought to be involved in neurodevelopmental disorders. Healthy astrocytes partially rescue Rett Syndrome...

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Literature Corpus work: 8e142bf9-cda6-594d-9ed2-9b471eba0fda
DOI: 10.1101/2023.04.29.538761

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