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Article

Extracellular Vesicles in Amyotrophic Lateral Sclerosis

31 Dec 2022

Abstract excerpt

Amyotrophic Lateral Sclerosis is a progressive neurodegenerative disease and is the most common adult motor neuron disease. The disease pathogenesis is complex with the perturbation of multiple pathways proposed, including mitochondrial dysfunction, RNA processing, glutamate excitotoxicity, endoplasmic reticulum stress, protein homeostasis and endosomal transport/extracellular vesicle (EV) secretion. EVs are...

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PMID: 36676070
DOI: 10.3390/life13010121

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