Article

Differential haplotype expression in class I MHC genes during SARS-CoV-2 infection of human lung cell lines

2022-11-21

Abstract excerpt

Cell entry of SARS-CoV-2 causes genome-wide disruption of the transcriptional profiles of genes and biological pathways involved in the pathogenesis of COVID-19. Expression allelic imbalance is characterized by a deviation from the Mendelian expected 1:1 expression ratio and is an important source of allele-specific heterogeneity. Expression allelic imbalance can be measured by allele-specific expression analysis...

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Literature Corpus work: c66b8931-90c5-5944-8156-8cbf5ad33004
DOI: 10.1101/2022.11.20.517193

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