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Genetic variability in COVID-19-related genes in the Brazilian population

2 Apr 2021

Abstract excerpt

Abstract SARS-CoV-2 utilizes the angiotensin-converting enzyme 2 (ACE2) receptor and transmembrane serine protease (TMPRSS2) to infect human lung cells. Previous studies have suggested that different host ACE2 and TMPRSS2 genetic backgrounds might contribute to differences in the rate of SARS-CoV-2 infection or COVID-19 severity. Recent studies have also shown that variants in 15 genes related to type I...

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PMID: 33824725
DOI: 10.1038/s41439-021-00146-w

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