Article

Arf family GTPases: roles in membrane traffic and microtubule dynamics

2005-10-26

Abstract excerpt

Database mining and phylogenetic analysis of the Arf (ADP-ribosylation factor) superfamily revealed the presence in mammals of at least 22 members, including the six Arfs, two Sars and 14 Arl (Arf-like) proteins. At least six Arf family members were found in very early eukaryotes, including orthologues of Arf, Sar, Arl2, Arl3, Arl6 and Arl8. While roles for Arfs in membrane traffic are well known, those for most o...

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Literature Corpus work: 13b371eb-bb4e-5c51-b15a-d01436036677
DOI: 10.1042/bst0331269

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