Article

Generating Human Gastruloids from Human Embryonic Stem Cells

2020-06-11

Abstract excerpt

<title>Abstract</title> <p>Gastruloids are aggregates of Pluripotent Stem Cells (PSCs) which, when exposed to differentiation medium and plated within defined conditions, undergo trilineage differentiation to all three germ layers (mesoderm, ectoderm and endoderm) with constitutive cell types organised spatiotemporally along 3 axes (Becarri et. al. 2018). They also undergo morphological shape changes including ax...

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Literature Corpus work: c661d5ed-033e-5243-b5df-a7aadaf0245b
DOI: 10.21203/rs.3.pex-812/v1

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