Article

Generation of human haploid neural stem cells from parthenogenetic embryonic stem cells

2022-12-07

Abstract excerpt

<title>Abstract</title><p>Recently, haploid embryonic stem cells (haESCs) have been established in many species and widely used in forward and reverse genetic screening. Differentiated haploid cell line types in mammals are lacking due to spontaneous diploidization during differentiation that compromises lineage-specific screens. Human embryonic stem cells are widely used in basic and preclinical research. In this...

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Literature Corpus work: c680d455-d6b5-5be1-bdce-031d885d1ebd
DOI: 10.21203/rs.3.rs-2332761/v1

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