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Derivation of trophoblast stem cells from human expanded potential stem cells

1 Jun 2023

Abstract excerpt

Human trophoblast development study has long been limited by the lack of suitable materials. Here we present a detailed protocol for the differentiation of human expanded potential stem cells (hEPSCs) into human trophoblast stem cells (TSCs) and for the subsequent establishment of TSC lines. The hEPSC-derived TSC lines can be continuously passaged and are functional in further differentiation into...

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PMID: 37300826
DOI: 10.1016/j.xpro.2023.102354

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