Article

iPSC Neurodegenerative Disease Initiative isogenic CAG repeat iPSC line for Huntington’s disease

2026-07-04

Abstract excerpt

<h4>STRUCTURED ABSTRACT</h4> <h4>Purpose of Research</h4> The generation of iPSC lines expressing 21, 56 and 79 glutamine repeats within the HTT protein and homozygous KO of HTT in the KOLF2.1J background as an additional disease series within the iPSC Neurodegenerative Disease Initiative (iNDI) collection. <h4>Major Findings</h4> All iPSCs, even those expressing long repeats of 79Q or HTT KO, were capable of...

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Literature Corpus work: c6506485-b443-5db7-b5c4-374576867fbe
DOI: 10.64898/2026.06.30.735662

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