Article

Cognitive decline heralds onset of symptomatic inherited prion disease

2020-09-15

Abstract excerpt

The clinical effectiveness of any disease-modifying treatment for prion disease, as for other neurodegenerative disorders, will depend on early treatment before damage to neural tissue is irrevocable. Thus, there is a need to identify markers which predict disease onset in healthy at-risk individuals. Whilst imaging and neurophysiological biomarkers have shown limited use in this regard, we recently reported progr...

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Literature Corpus work: c63d9523-3dea-5723-a492-c8e6da4fd030
DOI: 10.1101/2020.09.14.20194217

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