Article
Neuropsychological Symptoms in Sporadic Creutzfeldt-Jakob Disease Patients in Germany.
Journal of Alzheimer's disease : JAD - 1 Jan 2017
Krasnianski Anna, Bohling Geeske T, Heinemann Uta, Varges Daniela, Meissner Bettina, Schulz-Schaeffer Walter J, Reif Andreas, Zerr Inga
Abstract excerpt
BACKGROUND: The polymorphism at codon 129 of the prion protein gene (PRNP) and the PrPSc types 1 and 2 belong to a molecular classification of sporadic Creutzfeldt-Jakob disease (sCJD) that correlates well with the clinical and neuropathological phenotype of sCJD. OBJECTIVE: The aim of the study was to perform the first detailed evaluation of neuropsychological deficits in a large group of definite sCJD patients...
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