Article

Reduced frequency of clonal hematopoiesis in Parkinson’s disease patients

2023-05-07

Abstract excerpt

To test if clonal hematopoiesis of indeterminate potential (CHIP) is associated with the incidence of Parkinson’s Disease (PD), we analyzed blood whole exome sequencing data from 171 healthy controls and 335 PD subjects in the Parkinson’s Progression Markers Initiative. We observed an age-related increase of CHIP carriers in the healthy controls. Surprisingly, the percentage of CHIP carriers was significantly lowe...

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Literature Corpus work: c624e016-0c8c-50d3-95a6-a217c9606585
DOI: 10.1101/2023.05.04.539397

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