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Article

Increased epigenetic age and granulocyte counts in the blood of Parkinson's disease patients

9 Dec 2015

Abstract excerpt

It has been a long standing hypothesis that blood tissue of PD Parkinson's disease (PD) patients may exhibit signs of accelerated aging. Here we use DNA methylation based biomarkers of aging ("epigenetic clock") to assess the aging rate of blood in two ethnically distinct case-control data sets. Using n=508 Caucasian and n=84 Hispanic blood samples, we assess a) the intrinsic epigenetic age acceleration of blood...

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PMID: 26655927
DOI: 10.18632/aging.100859

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