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Article

Clonal haematopoiesis of indeterminate potential and risk of incident psychiatric disorders.

BMC medicine - 18 Feb 2026

Yu Yuefeng, Wan Chenyi, Li Jiang, Sun Ying, Yu Bowei, Tan Xiao, Wang Bin, Lu Yingli, Wang Ningjian

Abstract excerpt

BACKGROUND: Exploring the association of clonal haematopoiesis of indeterminate potential (CHIP) with psychiatric disorders (PDs) may help to elucidate the biological mechanisms underlying PDs. The study aimed to identify the specific PD subtypes associated with CHIP and gene-specific CHIP for each PD subtype. METHODS: A total of 360,451 participants from UK Biobank without PDs at baseline, aged 40-69 years and...

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Source

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Identifiers

PMID: 41709299
DOI: 10.1186/s12916-026-04720-3
PMCID: PMC13019851

Genes

DNMT3A
ASXL1
NF1
PPM1D
SF3B1
SRSF2
TET2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

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