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Article

Knockout of AMD-associated gene <i>POLDIP2</i> reduces mitochondrial superoxide in human retinal pigment epithelial cells

2022-07-06

Abstract excerpt

Genetic and epidemiologic studies have significantly advanced our understanding of the genetic factors contributing to age-related macular degeneration (AMD). In particular, recent expression quantitative trait loci (eQTL) studies have highlighted POLDIP2 as a significant gene that confers risk of developing AMD. However, the role of POLDIP2 in retinal cells such as retinal pigment epithelium (RPE) and how it co...

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Literature Corpus work
c61c6623-758d-533e-98cb-56bb74bd14b9
DOI
10.1101/2022.07.05.498910
Open publication

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Knockout of AMD-associated gene <i>POLDIP2</i> reduces mitochondrial superoxide in human retinal pigment epithelial cellsDOI 10.1101/2022.07.05.498910
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