Article

Two novel DnaJ chaperone proteins CG5001 and P58IPK regulate the pathogenicity of Huntington’s Disease

2024-05-02

Abstract excerpt

<title>Abstract</title> <p>Huntington’s disease (HD) is a rare neurodegenerative disease caused due to aggregation of Huntingtin (HTT) protein. This study involves cloning of 40 DnaJ chaperones from Drosophila, and overexpressing them in yeasts and fly models of HD. Accordingly, DnaJ chaperones were catalogued as enhancers or suppressors based on their growth phenotypes and aggregation properties. 2 of the chaper...

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Literature Corpus work: c5ffaaac-220a-5fe7-aef3-45028bbcd00d
DOI: 10.21203/rs.3.rs-4217686/v1

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Two novel DnaJ chaperone proteins CG5001 and P58IPK regulate the pathogenicity of Huntington’s DiseaseDOI 10.21203/rs.3.rs-4217686/v1Read

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