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Transcriptome analysis in <i>C. elegans</i> early embryos upon depletion of the Topoisomerase 2/condensin II axis

2024-10-18

Abstract excerpt

In C. elegans , the chromosome compaction factors topoisomerase 2 (TOP-2) and condensin II have been shown to globally repress transcription in multiple contexts. Our group has previously reported that TOP-2 and condensin II repress transcription in the C. elegans germline during larval starvation, oocyte maturation, and in germline progenitor cells of the early embryo. Here, we assess the transcriptome of early...

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Literature Corpus work
c5be8076-5a70-5c42-9419-d40f4c126c5b
DOI
10.1101/2024.10.17.618010
Open publication

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Transcriptome analysis in <i>C. elegans</i> early embryos upon depletion of the Topoisomerase 2/condensin II axisDOI 10.1101/2024.10.17.618010
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