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Histone methyltransferase MET-2 differentially regulates autosome and X-chromosome structure and transcription during meiosis in <i>C. elegans</i>

2026-07-29

Abstract excerpt

During meiosis, accurate chromosome segregation requires significant condensation and compaction. These processes are mediated by condensins, cohesins, and histone tail modifications. We identified that MET-2, a histone methyltransferase that catalyzes the dimethylation of histone H3 lysine 9 (H3K9me2), differentially impacts chromosome size in the male vs. female C. elegans germline. In met-2 null worms, autoso...

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Literature Corpus work
d8f580c1-4e21-5e51-b7c8-030a0d3f98a8
DOI
10.64898/2026.07.26.740854
Open publication

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