Article

Identification of mammalian-adapting mutations involved into antigenic change of H1N1 influenza virus

2020-08-05

Abstract excerpt

<title>Abstract</title> <p>Though the 2009 pandemic H1N1 virus has become a seasonal influenza A virus, continued host adaptation and antigenic drift may limit the effectiveness of current vaccines. Here, we assess viral antigenic change of a 2009 pandemic H1N1 virus (A/Changchun/01/2009) in the absence and presence of immune-mediated selective pressures and further identify the key amino acid substitutions invol...

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Literature Corpus work: c5b8ab4e-bcfa-5c2a-bc42-553adaf6408e
DOI: 10.21203/rs.3.rs-51173/v1

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