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Article

HA gene amino acid mutations contribute to antigenic variation and immune escape of H9N2 influenza virus.

Veterinary research - 15 Jun 2022

Zhu Rui, Xu Shunshun, Sun Wangyangji, Li Quan, Wang Shifeng, Shi Huoying, Liu Xiufan

Abstract excerpt

Based on differences in the amino acid sequence of the protein haemagglutinin (HA), the H9N2 avian influenza virus (H9N2 virus) has been clustered into multiple lineages, and its rapidly ongoing evolution increases the difficulties faced by prevention and control programs. The HA protein, a major antigenic protein, and the amino acid mutations that alter viral antigenicity in particular have always been of...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 35706014
DOI: 10.1186/s13567-022-01058-5
PMCID: PMC9202205

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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