Article

Single-Cell Analysis of Microglia and Monocyte Dynamics Uncover Distinct TNF-α-driven Neuroimmune Signatures after Intracerebral Hemorrhage

2024-12-24

Abstract excerpt

Innate immune cells contribute to both secondary brain injury and repair following intracerebral hemorrhage (ICH). However, the specific signaling pathways that govern initial inflammatory and subsequent reparative myeloid programs in living patients remain poorly understood. To better characterize mononuclear phagocyte cell changes over time, we generated a single-cell transcriptomic dataset of paired hematoma cl...

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Literature Corpus work: c57aeb2d-7e64-5976-9baa-95c579b6d4cc
DOI: 10.1101/2024.12.24.630187

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