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Comprehensive insight on immune landscape in intracerebral hemorrhage patients with single-cell RNA sequencing: from blood to hematoma

30 Jul 2025

Abstract excerpt

BACKGROUND: As limited medical interventions proved efficacy in intracerebral hemorrhage (ICH), the mechanisms underlying primary and secondary tissue injury remain poorly understood based on hematoma. In this study, we aimed to investigate the transcriptional profiles of immune cells from hematoma samples derived from ICH patients, which was rarely focused before. METHODS: Single cell RNA sequencing (scRNA-seq)...

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Share to Intracerebral and Subarachnoid Hemorrhage Research
Share to Neuroinflammation and Neurodegeneration Mechanisms
Share to Single-cell and spatial transcriptomics

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PMID: 40739271
DOI: 10.1186/s12974-025-03518-z

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

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