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Monocyte, neutrophil, and whole blood transcriptome dynamics following ischemic stroke

20 Feb 2023

Abstract excerpt

BACKGROUND: After ischemic stroke (IS), peripheral leukocytes infiltrate the damaged region and modulate the response to injury. Peripheral blood cells display distinctive gene expression signatures post-IS and these transcriptional programs reflect changes in immune responses to IS. Dissecting the temporal dynamics of gene expression after IS improves our understanding of immune and clotting responses at the...

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PMID: 36803375
DOI: 10.1186/s12916-023-02766-1

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