Back to search

Article

The Role of Tumor Necrosis Factor Signaling in Atherosclerosis and Stroke

2026-05-01

Abstract excerpt

<h4>Background</h4> Inflammation is an emerging target for stroke prevention, but additional therapeutic candidates are needed. Experimental and observational studies implicate tumor necrosis factor (TNF) in atherosclerotic plaque progression and cardiovascular events. We integrated plasma proteomics from population-based studies and prospective stroke cohorts with single-cell and spatial transcriptomic profiling...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
3a1f5a91-8ccd-511d-90fd-1588ed97e3ab
DOI
10.64898/2026.04.29.26352088
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
The Role of Tumor Necrosis Factor Signaling in Atherosclerosis and StrokeDOI 10.64898/2026.04.29.26352088
Single-Cell Analysis of Microglia and Monocyte Dynamics Uncover Distinct TNF-α-driven Neuroimmune Signatures after Intracerebral HemorrhageSemantic proximity
Effects of tumour necrosis factor on cardiovascular disease and cancer: A two-sample Mendelian randomization study.Semantic proximity
Association of Methylation Signals With Incident Coronary Heart Disease in an Epigenome-Wide Assessment of Circulating Tumor Necrosis Factor αSemantic proximity
The Role of Tnf and Soluble Tnf Receptors (TNFR1/2) as Therapeutic Targets for Inflammation Secondary to Intracerebral Stroke and HemorrhageSemantic proximity
Characterizing Stroke Clots Using Single-Cell SequencingSemantic proximity
Genetic variants of TNFSF4 and risk for carotid artery disease and stroke.Semantic proximity
Genetically Determined Levels of Circulating Cytokines and Risk of StrokeSemantic proximity
Single-cell RNA analysis reveals the cell atlas of human intracranial aneurysm and rupture-related inflammation featuresSemantic proximity
Decoding the transcriptome of atherosclerotic plaque at single-cell resolutionSemantic proximity
TNFR Pathway-Related Proteins and Recurrent Coronary Artery Disease EventsSemantic proximity
Microanatomy of the Human Atherosclerotic Plaque by Single-Cell Transcriptomics.Semantic proximity
Inflammatory cytokines are associated with stroke and risk factors of cerebrovascular diseases: a Mendelian randomization study.Semantic proximity
Select a neighboring publication to make it the new centre.