Article

The impact of non-cardiomyocyte <i>MYBPC3</i> expression on the development of hypertrophic cardiomyopathy

2026-04-23

Abstract excerpt

<h4>Introduction</h4> Hypertrophic Cardiomyopathy (HCM) is a disease defined by the development of left ventricle hypertrophy. One of the most commonly mutated genes in HCM is cardiac myosin binding protein C ( MYBPC3 ). MYBPC3 protein localizes to the cardiomyocyte sarcomere, but studies have reported detection of both MYBPC3 RNA and protein in non-cardiomyocyte cell populations. Therefore, it was unclear if...

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Literature Corpus work: c54a1ea2-36c1-5c25-8e7e-96741a23e59c
DOI: 10.64898/2026.04.20.718297

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