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Article

An Update on MYBPC3 Gene Mutation in Hypertrophic Cardiomyopathy.

International journal of molecular sciences - 22 Jun 2023

Tudurachi Bogdan-Sorin, Zăvoi Alexandra, Leonte Andreea, Țăpoi Laura, Ureche Carina, Bîrgoan Silviu Gabriel, Chiuariu Traian, Anghel Larisa, Radu Rodica, Sascău Radu Andy, Stătescu Cristian

Abstract excerpt

Hypertrophic cardiomyopathy (HCM) is the most prevalent genetically inherited cardiomyopathy that follows an autosomal dominant inheritance pattern. The majority of HCM cases can be attributed to mutation of the MYBPC3 gene, which encodes cMyBP-C, a crucial structural protein of the cardiac muscle. The manifestation of HCM's morphological, histological, and clinical symptoms is subject to the complex interplay of...

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Identifiers

PMID: 37445689
DOI: 10.3390/ijms241310510
PMCID: PMC10341819

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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