Article
MicroRNA transcriptome profiling in cardiac tissue of hypertrophic cardiomyopathy patients with MYBPC3 mutations.
Journal of molecular and cellular cardiology - 1 Dec 2013
Kuster Diederik W D, Mulders Joyce, Ten Cate Folkert J, Michels Michelle, Dos Remedios Cristobal G, da Costa Martins Paula A, van der Velden Jolanda, Oudejans Cees B M
Abstract excerpt
Hypertrophic cardiomyopathy (HCM) is predominantly caused by mutations in genes encoding sarcomeric proteins. One of the most frequent affected genes is MYBPC3, which encodes the thick filament protein cardiac myosin binding protein C. Despite the prevalence of HCM, disease pathology and clinical...
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