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Hypertrophic cardiomyopathy in MYBPC3 carriers in aging

11 Jan 2024

Abstract excerpt

Hypertrophic cardiomyopathy (HCM) is characterized by abnormal thickening of the myocardium, leading to arrhythmias, heart failure, and elevated risk of sudden cardiac death, particularly among the young. This inherited disease is predominantly caused by mutations in sarcomeric genes, among which those in the cardiac myosin binding protein-C3 (MYBPC3 ) gene are major contributors. HCM associated with MYBPC3...

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PMID: 38406555
DOI: 10.20517/jca.2023.29

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