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Article

Cardiac myosin-binding protein C (MYBPC3) in cardiac pathophysiology.

Gene - 1 Dec 2015

Carrier Lucie, Mearini Giulia, Stathopoulou Konstantina, Cuello Friederike

Abstract excerpt

More than 350 individual MYPBC3 mutations have been identified in patients with inherited hypertrophic cardiomyopathy (HCM), thus representing 40–50% of all HCM mutations, making it the most frequently mutated gene in HCM. HCM is considered a disease of the sarcomere and is characterized by left ventricular hypertrophy, myocyte disarray and diastolic dysfunction. MYBPC3 encodes for the thick filament associated...

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Source

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Identifiers

PMID: 26358504
DOI: 10.1016/j.gene.2015.09.008
PMCID: PMC6660134

Genes

MYBPC3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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