Article

3D Genome Analysis Identifies Enhancer Hijacking Mechanism for High-Risk Factors in Human T-Lineage Acute Lymphoblastic Leukemia

2020-03-12

Abstract excerpt

Recent studies have demonstrated that 3D genome alterations play important roles in tumorigenesis 1–3 , including the development of hematological malignancies 4–7 . However, how such alterations may provide key insights into T-lineage acute lymphoblastic leukemia (T-ALL) patients is largely unknown. Here, we report integrated analyses of 3D genome alterations and differentially expressed genes (DEGs) in 18 newl...

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Literature Corpus work: c5163458-d9c6-52c9-9407-050e9187b732
DOI: 10.1101/2020.03.11.988279

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3D Genome Analysis Identifies Enhancer Hijacking Mechanism for High-Risk Factors in Human T-Lineage Acute Lymphoblastic LeukemiaDOI 10.1101/2020.03.11.988279Read

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