Article

Clinicopathologic and molecular spectrum of gastrointestinal stromal tumor (GIST) with NTRK fusion and marked response to Larotrectinib in GIST with NTRK fusion: a case report

2025-09-30

Abstract excerpt

<title>Abstract</title> <p> Purpose This study aimed to characterize the clinicopathological, immunophenotypic, and molecular features of gastrointestinal stromal tumors (GISTs) harboring <italic>NTRK</italic> fusions and to evaluate their diagnostic, prognostic, and therapeutic implications. Methods Twenty-six cases of <italic>KIT/PDGFRA/SDH/BRAF</italic> wild-type GISTs were evaluated using pan-TRK immunoh...

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Literature Corpus work: c4cc45a8-d2a9-54ed-b3dd-481ff1cbd552
DOI: 10.21203/rs.3.rs-7615382/v1

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