Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Multidisciplinary consensus on optimising the detection of NTRK gene alterations in tumours

23 Feb 2021

Abstract excerpt

The recent identification of rearrangements of neurotrophic tyrosine receptor kinase (NTRK) genes and the development of specific fusion protein inhibitors, such as larotrectinib and entrectinib, have revolutionised the diagnostic and clinical management of patients presenting with tumours with these alterations. Tumours that harbour NTRK fusions are found in both adults and children; and they are either rare...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Chromatin Remodeling and Cancer
Share to Lung Cancer Treatments and Mutations
Share to Neurofibromatosis and Schwannoma Cases

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 33620682
DOI: 10.1007/s12094-021-02558-0

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Multidisciplinary consensus on optimising the detection of NTRK gene alterations in tumoursPMID 33620682Read ↗

NTRK gene fusions in solid tumors: agnostic relevance, prevalence and diagnostic strategiesSemantic proximity Read ↗

Testing algorithm for identification of patients with TRK fusion cancerSemantic proximity Read ↗

NTRK Fusions, from the Diagnostic Algorithm to Innovative Treatment in the Era of Precision MedicineSemantic proximity Read ↗

[Diagnosis and therapy of tumors with NTRK gene fusion].Semantic proximity Read ↗

NTRK Fusions in Central Nervous System Tumors: A Rare, but Worthy TargetSemantic proximity Read ↗

A review of NTRK fusions in cancerSemantic proximity Read ↗

Canadian Consensus for Biomarker Testing and Treatment of TRK Fusion Cancer in AdultsSemantic proximity Read ↗

Expert consensus on the diagnosis and treatment of NTRK gene fusion solid tumors in ChinaSemantic proximity Read ↗

Belgian expert consensus for tumor-agnostic treatment of NTRK gene fusion-driven solid tumors with larotrectinibSemantic proximity Read ↗

Canadian Consensus for Biomarker Testing and Treatment of TRK Fusion Cancer in Pediatric PatientsSemantic proximity Read ↗

Comprehensive genomic profiling identifies novel NTRK fusions in neuroendocrine tumorsSemantic proximity Read ↗

NTRK gene fusion testing and management in lung cancerSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.