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Expert consensus on the diagnosis and treatment of NTRK gene fusion solid tumors in China

20 Sept 2022

Abstract excerpt

Gene fusions can drive tumor development for multiple types of cancer. Currently, many drugs targeting gene fusions are being approved for clinical application. At present, tyrosine receptor kinase (TRK) inhibitors targeting neurotrophic tyrosine receptor kinase (NTRK) gene fusions are among the first "tumor agnostic" drugs approved for pan-cancer use. Representative TRK inhibitors, including larotrectinib and...

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PMID: 36127731
DOI: 10.1111/1759-7714.14644

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