Article

Bayesian Analysis of the Rate of Spontaneous Malignant Mesothelioma Among BAP1 Mutant Mice in the Absence of Asbestos Exposure

2024-10-07

Abstract excerpt

<title>Abstract</title> <p>Cancers of the mesothelium, such as malignant mesothelioma (MM), historically have been attributed solely to exposure to asbestos. Recent large scale genetic and genomic functional studies now show that approximately 20% of all human mesotheliomas are causally linked to highly penetrant inherited (germline) pathogenic mutations in numerous cancer related genes. The rarity of these mutat...

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Literature Corpus work: c452d2f1-343e-5fac-8f01-85a211a2a2f0
DOI: 10.21203/rs.3.rs-4987023/v1

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