Article

Fluorinated RNA origami enables serum-stable nanodevices for sensing and targeting

2026-03-04

Abstract excerpt

Chemically modified RNAs with increased stability and reduced immunogenicity have transformed RNA therapeutics. Rational RNA design methods, including RNA origami, seek to further extend RNA medicine and biotechnology by encoding advanced functions such as signalling, targeting, and controlled release within the RNA polymer. However, current design methods lack the ability to integrate chemical modification or pre...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: c427658d-a475-5ec0-bf14-ab98501b881a
DOI: 10.64898/2026.03.04.709525

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Fluorinated RNA origami enables serum-stable nanodevices for sensing and targetingDOI 10.64898/2026.03.04.709525Read

A spring-loaded and leakage-tolerant synthetic gene switch for in-vitro detection of DNA and RNASemantic proximity Read

RNA versatility, flexibility, and thermostability for practice in RNA nanotechnology and biomedical applications.Semantic proximity Read

Engineering Versatile Two-Dimensional Nanobody-Origami Architectures for Enhanced Antiviral ActivitySemantic proximity Read

Fabrication of stable and RNase-resistant RNA nanoparticles active in gearing the nanomotors for viral DNA packaging.Semantic proximity Read

Visualizing and Quantifying microRNA Induced DNA Origami Separation at the NanoscaleSemantic proximity Read

Visualizing single-base RNA mutations in living cells through DNA nanostructure-mediated amplificationSemantic proximity Read

Cell-free transcriptional regulation via nucleic-acid-based transcription factorsSemantic proximity Read

Development of nucleic acid-based nanoplatforms for applications in disease diagnostics and the study of nanomaterials-protein interactionsSemantic proximity Read

Targeted RNA Condensation in Living Cells via Genetically Encodable Triplet Repeat TagsSemantic proximity Read

Engineering of a DNA/γPNA Hybrid Nanoreporter for ctDNA Mutation Detection via γPNA Urinalysis.Semantic proximity Read

Simultaneous identification of viruses and viral variants with programmable DNA nanobaitSemantic proximity Read

Systematic Mutation and Unnatural Base Pair Incorporation Improves Riboswitch-Based Biosensor Response Time.Semantic proximity Read