Article

Ex vivo analysis of human memory CD4 T cells specific for hepatitis C virus using MHC class II tetramers

2003-09-15

Abstract excerpt

Containment of hepatitis C virus (HCV) and other chronic human viral infections is associated with persistence of virus-specific CD4 T cells, but ex vivo characterization of circulating CD4 T cells has not been achieved. To further define the phenotype and function of these cells, we developed a novel approach for the generation of tetrameric forms of MHC class II/peptide complexes that is based on the cellular pe...

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Literature Corpus work: c426e2a1-8304-5799-8b44-468ca9b813aa
DOI: 10.1172/jci200318509

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