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Article

Virus-Specific CD4+ T Cells Have Functional and Phenotypic Characteristics of Follicular T-Helper Cells in Patients With Acute and Chronic HCV Infections.

Gastroenterology - 1 Mar 2016

Raziorrouh Bijan, Sacher Kathrin, Tawar Rajiv G, Emmerich Florian, Neumann-Haefelin Christoph, Baumert Thomas F, Thimme Robert, Boettler Tobias

Abstract excerpt

BACKGROUND & AIMS: Follicular T-helper (Tfh) cells contribute to pathogen-specific antibody responses by providing maturation signals to B cells. In mice with viral infections, virus-specific Tfh cells expand and are required to contain the infection. However, less is known about human virus-specific Tfh cells or their functions during infection. We investigated whether virus-specific CD4+ T cells from patients...

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Identifiers

PMID: 26584604
DOI: 10.1053/j.gastro.2015.11.005

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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