Article

Lysophosphatidylcholine acyltransferase 1 controls the mitochondrial reactive oxygen species generation and survival of the retinal photoreceptor cells

2021-10-07

Abstract excerpt

<h4>ABSTRACT</h4> Due to the high energy demands and characteristic morphology, retinal photoreceptor cells require a specialized lipid metabolism for survival and function. Accordingly, dysregulation of lipid metabolism leads to the photoreceptor cell death and retinal degeneration. Mice with a frameshift mutation of lysophosphatidylcholine acyltransferase 1 ( Lpcat1 ), which produces saturated phosphatidylchol...

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Literature Corpus work: c40993ae-c776-530c-9f99-5b4655674cae
DOI: 10.1101/2021.10.06.463439

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