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Article

Loss of lysophosphatidylcholine acyltransferase 1 leads to photoreceptor degeneration in rd11 mice

16 Aug 2010

Abstract excerpt

Retinal degenerative diseases, such as retinitis pigmentosa and Leber congenital amaurosis, are a leading cause of untreatable blindness with substantive impact on the quality of life of affected individuals and their families. Mouse mutants with retinal dystrophies have provided a valuable resource to discover human disease genes and helped uncover pathways critical for photoreceptor function. Here we show that...

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Identifiers

PMID: 20713727
DOI: 10.1073/pnas.1002897107

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Loss of lysophosphatidylcholine acyltransferase 1 leads to photoreceptor degeneration in rd11 micePMID 20713727Read ↗

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