Article

PCYT1A deficiency disturbs fatty acid metabolism and induces ferroptosis in mice retina

2023-10-10

Abstract excerpt

<title>Abstract</title> <p>Inherited retinal dystrophies (IRDs) encompass a group of debilitating visual disorders characterized by the progressive degeneration of photoreceptors, ultimately leading to blindness. Among the causes of this condition, mutations in the <italic>PCYT1A</italic> gene have been identified, which encodes the rate-limiting enzyme responsible for phosphatidylcholine (PC) <italic>de novo</it...

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Literature Corpus work: df85f24e-edbb-5cf0-9fca-fedc6fadc4bc
DOI: 10.21203/rs.3.rs-3394581/v1

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