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Article

Role of Mitochondria in Retinal Pigment Epithelial Aging and Degeneration

15 Jul 2022

Abstract excerpt

Retinal pigment epithelial (RPE) cells form a monolayer between the neuroretina and choroid. It has multiple important functions, including acting as outer blood-retina barrier, maintaining the function of neuroretina and photoreceptors, participating in the visual cycle and regulating retinal immune response. Due to high oxidative stress environment, RPE cells are vulnerable to dysfunction, cellular senescence,...

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Identifiers

PMID: 35912040
DOI: 10.3389/fragi.2022.926627

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