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Article

Drosophila fatty acid transport protein regulates rhodopsin-1 metabolism and is required for photoreceptor neuron survival.

PLoS genetics - 1 Jan 2012

Dourlen Pierre, Bertin Benjamin, Chatelain Gilles, Robin Marion, Napoletano Francesco, Roux Michel J, Mollereau Bertrand

Abstract excerpt

Tight regulation of the visual response is essential for photoreceptor function and survival. Visual response dysregulation often leads to photoreceptor cell degeneration, but the causes of such cell death are not well understood. In this study, we investigated a fatty acid transport protein (fatp) null mutation that caused adult-onset and progressive photoreceptor cell death. Consistent with fatp having a role...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 22844251
DOI: 10.1371/journal.pgen.1002833
PMCID: PMC3405995

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