Article

MLKL deficiency alleviates neuroinflammation and motor deficits in the α-synuclein transgenic mouse model of Parkinson’s disease

2023-06-28

Abstract excerpt

<title>Abstract</title> <p>Parkinson’s disease (PD), one of the most devastating neurodegenerative brain disorders, is characterized by the progressive loss of dopaminergic neurons in the substantia nigra (SN) and deposits of α-synuclein aggregates. Currently, pharmacological interventions for PD remain inadequate. The cell necroptosis executor protein MLKL (Mixed-lineage kinase domain-like) is involved in variou...

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Literature Corpus work: c3d0795c-a1ef-5f73-9510-a436677be2a1
DOI: 10.21203/rs.3.rs-2996654/v1

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