Article
Instant fluorescence lifetime imaging microscopy reveals mechano-metabolic reprogramming of stromal cells in breast cancer peritumoral microenvironments
2025-05-30
Abstract excerpt
The breast peritumor microenvironment (pTME) is increasingly recognized as a mediator of breast cancer progression and treatment resistance. However, if and how growth-induced tumor compressive forces (i.e., solid stresses) influence the breast pTME remains unclear. Here we show using instant fluorescence lifetime imaging microscopy (FLIM)—a frequency-domain FLIM system capable of simultaneous image acquisition an...
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Identifiers and source
- Literature Corpus work
- c3a2ff6f-cbf2-5f0b-b180-40eb54d7b3bf
- DOI
- 10.1101/2025.05.28.656717
