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Instant fluorescence lifetime imaging microscopy reveals mechano-metabolic reprogramming of stromal cells in breast cancer peritumoral microenvironments

2025-05-30

Abstract excerpt

The breast peritumor microenvironment (pTME) is increasingly recognized as a mediator of breast cancer progression and treatment resistance. However, if and how growth-induced tumor compressive forces (i.e., solid stresses) influence the breast pTME remains unclear. Here we show using instant fluorescence lifetime imaging microscopy (FLIM)—a frequency-domain FLIM system capable of simultaneous image acquisition an...

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Literature Corpus work
c3a2ff6f-cbf2-5f0b-b180-40eb54d7b3bf
DOI
10.1101/2025.05.28.656717
Open publication

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Instant fluorescence lifetime imaging microscopy reveals mechano-metabolic reprogramming of stromal cells in breast cancer peritumoral microenvironmentsDOI 10.1101/2025.05.28.656717
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