Article

Divergent effects of HLA-DQA1:p.Gln198Glu on trajectory in inflammatory bowel disease

2026-05-11

Abstract excerpt

<title>Abstract</title> <p> Inflammatory bowel disease (IBD) is a polygenic condition, influenced by environmental factors, and demonstrating marked phenotypic heterogeneity. While genetic susceptibility is well characterised, genetic determinants of disease severity and progression remain unclear. We report the novel divergent effects of <italic>HLA-DQA1:p.Gln198Glu</italic> , associated with increased risk o...

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Literature Corpus work: c3883719-b953-5beb-8632-328e2e394cb0
DOI: 10.21203/rs.3.rs-9569016/v1

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