Article
HLA-DQ genotype distribution and risk evaluation of celiac disease in Northwest China.
Scandinavian journal of gastroenterology - 1 May 2023
Shi Tian, Liu Weidong, Li Ting, Liu Huan, Hui Wenjia, Lin Qiang, Han Xiaojiang, Gao Feng
Abstract excerpt
BACKGROUND: Celiac disease (CD) is an autoimmune small bowel disease. Genetic susceptibility for CD is mainly determined by the human leukocyte antigen (HLA)-DQ haplotypes. The risk of CD conferred by HLA genotypes varies geographically and across populations, however, this has not yet been documented in Chinese patients with CD. AIMS: To investigate the distribution of HLA-DQ and the related risks of CD...
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