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Article

DNA polymorphisms predict time to progression from uncomplicated to complicated Crohn's disease.

European journal of gastroenterology & hepatology - 1 Apr 2018

Pernat Drobež Cvetka, Repnik Katja, Gorenjak Mario, Ferkolj Ivan, Weersma Rinse K, Potočnik Uroš

Abstract excerpt

OBJECTIVE: Most patients with Crohn's disease (CD) are diagnosed with the uncomplicated inflammatory form of the disease (Montreal stage B1). However, the majority of them will progress to complicated stricturing (B2) and penetrating (B3) CD during their lifetimes. The aim of our study was to identify the genetic factors associated with time to progression from uncomplicated to complicated CD. PATIENTS AND...

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Source

Identifiers

PMID: 29293112
DOI: 10.1097/MEG.0000000000001055

Genes

BRD2
PPARA
PUDP
RASGRP1
SULF2
XPO1
ZBTB44

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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